Real Time Genomics Licenses RTG v2.0 Software to the Genome Center at Washington University
RTG v2.0 software to accelerate production and analysis of metagenomics sequence data on the Human Microbiome Project (HMP)
SAN FRANCISCO, California - Real Time Genomics, Inc. today announced that it has licensed its newly introduced RTG v2.0 sequence data analysis software to The Genome Center at Washington University in St. Louis (GCWU). The GCWU has licensed a set of functions specifically for processing sequence data in a data production and analysis pipeline for the Human Microbiome Project (HMP).
The licensed functionality includes sequence search and alignment software for nucleotide and protein similarity search. A read mapping function will be used for human contaminant filtering, and species identification in viral and bacterial databases. A protein search function will search translated nucleotide sequence against any protein database of interest.
The GCWU had early access to RTG software from Real Time Genomics during the product's development phase, which proved beneficial to both parties. Real Time Genomics delivered a protein database search solution that exceeded requirements established by BLASTX for search sensitivity, accuracy and speed. The GCWU was able to orient the Real Time Genomics development team, computer science PhDs with expertise in machine learning and sequence search, towards solving the critical computational analysis problem of protein similarity search.
"We produce thousands of metagenomics data sets in a few months, and it would take a decade or more to analyze these on a large cluster with BLASTX and other existing software," said George Weinstock, Associate Director of The Genome Center. "Real Time Genomics proved to us that RTG software was a reliable, accurate alternative to these programs that could reduce processing time by two orders of magnitude. This allows us to perform analysis on a comparable time frame as data production."
"The Genome Center at Washington University set an extremely high bar for sensitivity and accuracy in nucleotide and protein similarity search," said Graham Gaylard, CEO of Real Time Genomics. "We knew that we could solve their hard problems, which is why we took on the challenge."
Background Information
The NIH-funded Human Microbiome Project (HMP) promises to advance science towards the understanding, diagnosis and treatment of disease. For more information about The Genome Center at Washington University and its participation in the HMP, please refer to these bookmarked websites at delicious.com.
The Genome Center at Washington University
The Genome Center is a world leader in the fast-paced, constantly changing field of genomics. A truly unique institution, The Genome Center is pushing the limits of academic research by creating, testing, and implementing new approaches to the study of biology with the goal of understanding human health and disease, as well as evolution and the biology of other organisms. As one of only three NIH funded large-scale sequencing centers in the United States, The Genome Center is helping to lead the way in high-speed, comprehensive genomics. Since its inception in 1993, The Genome Center has played a vital role in the field of genome sequencing, receiving over $800 million in funding. The Genome Center began as a key player in the Human Genome Project, contributing 25 percent of the finished sequence. The Genome Center's research currently includes The Cancer Genome Atlas project, to sequence the DNA of adult cancer patients and their tumors to identify the genetic changes important to cancer; the Human Microbiome Project, to sequence communities of bacteria and viruses involved in human health and disease; and the 1,000 Genomes Project, to catalog the immense human variation written into the genetic code.
Real Time Genomics, Inc.
Real Time Genomics offers solutions for deep genomic analysis to researchers who use high throughput sequencing technologies. These solutions include RTG sequence data analysis software in read mapping, variant detection, protein search and metagenomics product packages. Patented pattern search technology from the company enables accurate sequence search and alignment with a unique combination of speed and sensitivity. Real Time Genomics is a private, San Francisco based company backed by investment from Catamount Ventures and Lightspeed Venture Partners.
Contact Information
Stewart Noyce
Real Time Genomics, Inc.
phone: 415.441.2466
e-mail: stewart@realtimegenomics.com
